Upgrade your reverse transcription, starting at $2 a sample.
MTP is an oligo pool for targeted reverse transcription. A drop-in primer replacement that captures only the RNAs you want, for any organism, without new equipment or added hands-on time.
Built for Any Organism
Neurospora, dengue, water buffalo — if it has a reference genome, we can design an MTP for it. And as your assay evolves, so can your primers: add targets, remove background RNAs, and fine-tune coverage without starting over.
Just an Oligo Pool
Chemically, the MTP is simply a large oligo pool that slots directly into your existing reverse transcription step. No new instruments, no added hands-on time, no workflow revalidation. The complexity is in the design and synthesis.
Beyond Poly(A)
Target any RNA species whether polyadenylated or not. From 500 to 30,000 unique targets, with fine-grained control over up to 5,000 off-target sequences. lncRNAs, circular RNAs, viral transcripts are all within reach.
Applications
One platform for the whole tree of life.
Host-Pathogen & Host-Vector
Multi-genome MTP pools give balanced transcriptome coverage across host and pathogen in a single reaction, resolving interactions that are invisible when each is sequenced separately. Target the pathogen over the host background, or throw in a selection of important host genes to highlight host-pathogen interactions.
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Multi-Targeted Priming Spotlight
Tick — Borrelia & Fungi
I. scapularis · B. burgdorferi · M. anisopliae
Targets the Borrelia and fungal transcriptomes from within the tick midgut, enabling simultaneous profiling of a bacterial pathogen and fungal co-inhabitant within their arthropod host.
Off-target controls suppress background signal and improve on-target enrichment specificity.
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All custom MTP pools are designed to your exact specifications. Start a custom request →
Multi-Targeted Priming (MTP) is changing RNA-seq
Download our MTP product overview for Reverse Transcription. Keep using your favorite library prep kits, just ditch the old primers for MTP.
Download Tech SheetThe Problem
Oligo(dT) hasn't changed since the 1970s.
Standard approaches have well-understood limitations — MTP was built to address each of them without adding complexity to your workflow.
Criteria
Oligo(dT)
Random Hexamers
Targeted Panels
Ribo Depletion & Hybrid Capture
MTP
RNA Class Access
lncRNA, circRNA, viral, non-polyadenylated
Target Specificity
Signal-to-noise, selectivity over background
Genome-wide Scalability
Targeted panels to whole transcriptome
Cost Efficiency
Reagent cost, sample requirements, sequencing depth
Workflow Simplicity
Drop-in replacement, no new instruments
Verdict
and use MTP
RNA Class Access
lncRNA, circRNA, viral, non-polyadenylated
Target Specificity
Signal-to-noise, selectivity over background
Genome-wide Scalability
Targeted panels to whole transcriptome
Cost Efficiency
Reagent cost, sample requirements, sequencing depth
Workflow Simplicity
Drop-in replacement, no new instruments
Stop Compromising and use MTP
The clear winner across every dimension.
The most important step in RNA-seq now starts at $2 a sample. Make it count.
Drop MTP into your next experiment and capture the biology you've been missing.
Drop-in replacement · No new instruments · Any organism