Upgrade your reverse transcription, starting at $2 a sample.
MTP is an oligo pool for targeted reverse transcription. A drop-in primer replacement that captures only the RNAs you want, for any organism, without new equipment or added hands-on time.
Built for Any Organism
Neurospora, dengue, water buffalo — if it has a reference genome, we can design an MTP for it. And as your assay evolves, so can your primers: add targets, remove background RNAs, and fine-tune coverage without starting over.
Just an Oligo Pool
Chemically, the MTP is simply a large oligo pool that slots directly into your existing reverse transcription step. No new instruments, no added hands-on time, no workflow revalidation. The complexity is in the design and synthesis.
Beyond Poly(A)
Target any RNA species whether polyadenylated or not. From 500 to 30,000 unique targets, with fine-grained control over up to 5,000 off-target sequences. lncRNAs, circular RNAs, viral transcripts are all within reach.
Applications
One platform for the whole tree of life.
Host-Pathogen & Host-Vector
Multi-genome MTP pools give balanced transcriptome coverage across host and pathogen in a single reaction, resolving interactions that are invisible when each is sequenced separately. Target the pathogen over the host background, or throw in a selection of important host genes to highlight host-pathogen interactions.
Explore host-pathogen MTP1 / 7
MTP Spotlight
Custom-designed for complex biology.
MTP pools built for real research problems — from tick midguts to coral holobionts.
Tick — Borrelia & Fungi
I. scapularis · B. burgdorferi · M. anisopliae
Targets the Borrelia and fungal transcriptomes from within the tick midgut, enabling simultaneous profiling of a bacterial pathogen and fungal co-inhabitant within their arthropod host.
Off-target controls are deliberately included to suppress background signal and improve on-target enrichment specificity.
Multi-Stage Malaria
P. falciparum · Anopheles · Human
Separate enrichment solutions for malaria in human host samples and malaria in mosquito vector samples, resolving stage-specific gene expression throughout the parasite lifecycle.
Danio sciRNA-seq
D. rerio
Targeted enrichment of transcription factors and Hox genes during zebrafish embryogenesis, capturing the regulatory landscape of developmental patterning at single-cell resolution.
Respiratory Aspergillus
Aspergillus · Rat
Simultaneous enrichment of host immune response and Aspergillus transcriptome from respiratory samples, resolving the molecular dynamics of fungal lung infection.
Neurospora
N. crassa
A foundational application of multi-targeted priming — targeted transcriptome profiling in a key model organism for circadian biology, gene regulation, and fungal development.
Coral & Fungi
Stylophora · Aspergillus · Aureobasidium · Candida · Cladosporium · Filobasidium · Penicillium · Sarocladium · Stachybotrys · Stemphylium
Joint transcriptome profiling of coral host, dinoflagellate symbiont, and associated fungal taxa — capturing the molecular cross-talk underlying symbiosis and its breakdown under thermal stress.
Human
H. sapiens
A comprehensive application of multi-targeted priming — targeted transcriptome profiling in the primary reference genome for biomedical research, clinical genetics, and disease biomarker discovery.
Anemone — Vibrio
N. vectensis · V. cholerae
Paired host-microbe enrichment to characterize the molecular dialogue in a cnidarian-bacterial association — simultaneous coverage of anemone host and Vibrio pathogen transcriptomes.
Grapevine
V. vinifera
An essential application of multi-targeted priming for targeted transcriptome profiling in a premier agricultural crop for viticulture research, fruit development, and environmental stress adaptation.
Plant Root — Trichoderma
A. thaliana · T. harzianum
Joint transcriptome profiling of plant host and biocontrol fungal partner, capturing the molecular cross-talk underlying growth promotion and pathogen resistance in the rhizosphere.
All custom MTP pools are designed to your exact specifications. Start a custom request →
Multi-Targeted Priming (MTP) is changing RNA-seq
Download our MTP product overview for Reverse Transcription. Keep using your favorite library prep kits, just ditch the old primers for MTP.
Download Tech SheetThe Problem
Oligo(dT) hasn't changed since the 1970s.
Standard approaches have well-understood limitations — MTP was built to address each of them without adding complexity to your workflow.
Criteria
Oligo(dT)
Random Hexamers
Targeted Panels
Ribo Depletion & Hybrid Capture
MTP
RNA Class Access
lncRNA, circRNA, viral, non-polyadenylated
Target Specificity
Signal-to-noise, selectivity over background
Genome-wide Scalability
Targeted panels to whole transcriptome
Cost Efficiency
Reagent cost, sample requirements, sequencing depth
Workflow Simplicity
Drop-in replacement, no new instruments
Verdict
and use MTP
RNA Class Access
lncRNA, circRNA, viral, non-polyadenylated
Target Specificity
Signal-to-noise, selectivity over background
Genome-wide Scalability
Targeted panels to whole transcriptome
Cost Efficiency
Reagent cost, sample requirements, sequencing depth
Workflow Simplicity
Drop-in replacement, no new instruments
Stop Compromising and use MTP
The clear winner across every dimension.
Ready to upgrade your reverse transcription?
Starting at $2 a sample. Drop-in replacement. No new instruments.
The most important step in RNA-seq now starts at $2 a sample. Make it count.
Drop MTP into your next experiment and capture the biology you've been missing.
Drop-in replacement · No new instruments · Any organism